Vitamin E Deficiency: A Threat to Specific Population Groups

Vitamin E is a crucial fat-soluble antioxidant that plays a vital role in protecting cells from oxidative stress. While a balanced diet usually provides sufficient vitamin E, certain population groups may be at risk of deficiency. In this article, we will explore the groups that are particularly vulnerable to vitamin E deficiency and the potential consequences of inadequate intake.

  1. Infants and Children:
    Infants who are exclusively breastfed and children with restrictive diets may be at risk of vitamin E deficiency. Since vitamin E is found in oils, nuts, and seeds, infants and children who do not have a varied diet may not receive an adequate amount of this essential vitamin, potentially impacting their growth and development.
  2. Individuals with Fat Malabsorption Issues:
    Vitamin E is a fat-soluble vitamin, meaning it requires the presence of dietary fat for absorption. Individuals with conditions that affect fat absorption, such as cystic fibrosis, celiac disease, or certain liver disorders, may struggle to absorb and utilize vitamin E properly. This can lead to a deficiency over time.
  3. Premature Infants:
    Premature infants, born before completing the full term, often have lower stores of vitamin E. This is because the last trimester of pregnancy is critical for the accumulation of this vitamin. Premature infants may require vitamin E supplementation to support their antioxidant defenses and overall development.
  4. People with Certain Genetic Disorders:
    Some rare genetic disorders, such as ataxia with vitamin E deficiency (AVED) or abetalipoproteinemia, impair the body’s ability to absorb and transport vitamin E. Individuals with these conditions may require specialized medical attention and vitamin E supplementation to prevent the adverse effects of deficiency.
  5. Older Adults:
    Aging can affect the body’s ability to absorb and utilize nutrients efficiently. Older adults may be at risk of vitamin E deficiency due to factors such as reduced dietary intake, impaired digestion, and certain medications that interfere with vitamin absorption. Adequate intake becomes especially important for maintaining cognitive function and preventing age-related diseases.

Consequences of Vitamin E Deficiency:

  1. Neurological Issues:
    Vitamin E is crucial for maintaining the health of nerve cells. Deficiency may lead to neurological symptoms such as muscle weakness, impaired coordination, and, in severe cases, nerve damage.
  2. Immune System Impairment:
    Vitamin E plays a role in supporting the immune system. A deficiency may compromise the body’s ability to fend off infections and illnesses.
  3. Vision Problems:
    Adequate levels of vitamin E are essential for eye health. Deficiency may contribute to vision problems, particularly retinal degeneration.


While vitamin E deficiency is relatively uncommon, certain population groups are more susceptible to inadequate intake. Maintaining a well-balanced diet that includes sources of vitamin E, such as nuts, seeds, and oils, is crucial for overall health. For individuals at higher risk, consultation with healthcare professionals and, if necessary, vitamin E supplementation can help address potential deficiencies and mitigate associated health risks.

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